A Secret Weapon For ceesdekker.net
A Secret Weapon For ceesdekker.net
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‘Of course, that's about ideal. I search for a Bodily knowledge of Organic units inside of a bottom-up way. I believe you could potentially distinguish a few strains of investigation in my team in the intervening time. The initial fears chromosome framework: how do you obtain a metre-long DNA polymer folded and organised in this type of microscopic cell? We've created visualisation procedures that allow us to review how, for example, SMC proteins loop DNA (video clip on Youtube) to be able to Make up chromosomes.
But how do morality, the dignity of your individual, my practical experience on the which means of lifestyle, abide by with the movement of atoms? A purely naturalistic perspective fails below; a Christian viewpoint, I think, is a way more sensible approach to interpret these aspects of reality.’
[Laughs] ‘It had been absolutely an awesome hazard! At some time, I had been perfectly mindful that it could go Mistaken and that I could turn out to be much less successful, but I just disregarded that. Curiosity has normally been my strongest driving pressure. And fortuitously it all labored out.’
Our operate was promptly adopted up by Some others, most notably by Phaedon Avouris and colleagues at IBM, who in Oct 1998 released their conclusions on transistors comprised of one- and multi-walled carbon nanotubes in Used Physics Letters.
2015, discovery that condensin is usually a hugely flexible protein composition; and 1st detection of DNA knots making use of nanopores
Direct immobilization of indigenous yeast iso-1 cytochrome c on bare gold: quickly electron relay to redox enzymes and zeptomole protein-movie voltammetry
What distinguishes biology from chemistry is usually that these elements alongside one another make up a residing procedure. The key of reported existence, I do think, lies within the interactions, the interplay of Those people molecules. The big query regarding the origin of everyday living continues to be unanswered. How did we at any time evolve from easy molecules in the extremely elaborate techniques we see nowadays? We don't know. I need to operate on these kinds of massive, open up questions.’
2011, initial in vitro measurements of transport throughout a single biomimetic nuclear pore complex; enhancement of multiplexed magnetic tweezers for kilo-molecule experiments; and fixed the system of homology recognition in DNA homologous recombination
The rotors harness Vitality from a nanoscale h2o and ion stream which ceesdekker.net is created by a static chemical or electrochemical probable gradient inside the nanopore, that are founded by way of a salt gradient or applied voltage, respectively. These synthetic nanoengines self-organize and work autonomously in physiological situations, suggesting methods to developing Vitality-transducing motors at nanoscale interfaces.
There was one issue even though — we did not observe any measurable electrical conduction from the single polymer molecules. We concluded that at the single-molecule degree, conducting polymers have been in fact not these good conductors, which was rather disappointing. We thus broadened our see to try to locate far more promising molecules.
‘The concept that There may be this kind of factor like a starting, a major bang, is already an interesting signpost to take into account that there was a creator. But additional generally, and on the basis of pure rationality, I also arrive at a Christian interpretation of actuality. An atheistic worldview can be a naturalistic worldview: basically, you will discover only atoms and purely natural forces that we can easily evaluate.
Afterwards we spoke once more briefly due to the fact Dekker felt that our dialogue of his religion quickly became purely philosophical, whereas Furthermore, it concretely can help him in his function.
2008, initial observation of protein-coated DNA translocation by means of nanopores; settled the origin from the electrophoretic force on DNA in nanopores; discovered a significant velocity maximize of microtubules in electric powered fields; learned an anomalous electro-hydrodynamic orientation of microtubules; and solved the origin of sound in carbon nanotubes in liquid
Dekker heeft fundamentele ontdekkingen gedaan op het gebied van koolstof nanobuisjes. Mede vanwege deze werkzaamheden is hij al jaren de meest geciteerde fysicus in Nederland. Tegenwoordig onderzoekt hij satisfied enkel-molecuultechnieken de biofysica van moleculen in de biologische cel. Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond clever design in 2005. (nl)